What does 'increased tolerance' mean?
Direct Answer
Increased tolerance refers to a biological adaptation where the body requires larger amounts of a substance to achieve the same effect previously attained with smaller amounts. This happens as the body's systems become less responsive to the substance over time. Increased tolerance is a physiological phenomenon and does not necessarily equate to addiction.
Common Misunderstandings
["It is often misunderstood that increased tolerance automatically means someone is addicted. While tolerance can be a component of substance use disorders, it can also occur with prescribed medications used as directed, such as certain painkillers or antidepressants, without the presence of addiction.","Another misconception is that experiencing tolerance means a person has poor willpower or is intentionally seeking more of a substance. Tolerance develops physiologically and is not a measure of an individual's moral character or control over substance use.","Some believe that if tolerance develops, a substance is no longer effective. This is not entirely true; while the original dose may be less effective, increased dosages can often still achieve the desired therapeutic or psychoactive effects, though this carries increased risks."]
In Practice
When a person develops increased tolerance, the initial dose of a substance may no longer produce the desired effect. This can lead to a person using more of the substance in an attempt to achieve the original effect. It is a common physiological response to repeated substance exposure. For example, a person prescribed a pain medication might find over time that the same dose provides less pain relief. In such cases, a healthcare provider might adjust the dosage. Conversely, an individual using a substance recreationally might increase their intake to achieve the desired psychological effects.
What This Does NOT Mean
["This does not mean that a person with increased tolerance is automatically addicted. Addiction involves compulsive substance seeking and use despite harmful consequences, along with impaired control, which is distinct from physical tolerance.","This does not include behavioral dependence, which is a psychological reliance on a substance or activity. Increased tolerance is primarily a physiological adaptation, though it can occur concurrently with psychological dependence.","This does not guarantee that withdrawal symptoms will occur if substance use is stopped. While tolerance often precedes physical dependence and withdrawal, the two are distinct concepts, and tolerance can exist without a full withdrawal syndrome."]
Scope
This information is for reference purposes only and does not constitute medical or clinical advice.