What is tolerance in substance use?
Direct Answer
Tolerance, in the context of substance use, refers to a diminished response to a substance over time. This means that a larger amount of the substance is required to achieve the same effect that was once produced by a smaller amount. It is a physiological adaptation of the body.
Common Misunderstandings
People sometimes believe that developing tolerance automatically means addiction. However, tolerance is a physiological response and does not, by itself, equate to addiction. Addiction involves compulsive substance seeking and use despite harmful consequences, which is distinct from needing more of a substance for a desired effect.
Another misunderstanding is that tolerance always implies illicit drug use. Tolerance can develop with various substances, including prescribed medications. This development does not necessarily indicate misuse or dependence in all cases.
In Practice
If a person develops tolerance, they may find that their usual dosage of a substance no longer produces the previously experienced effect. This can lead to increased intake if the initial effect is sought again.
For example, over time, a person using certain prescribed pain medications might find that the initial dosage provides less pain relief. A person consuming alcohol might find that more drinks are needed to feel the same effects as before. Tolerance is a physical adjustment. It refers to the body's adaptation.
What This Does NOT Mean
This does not mean that a person with tolerance is addicted. Addiction includes behavioral components like continued use despite negative consequences, which differs from a purely physiological adaptation.
This does not include all forms of decreased response to a substance. For instance, sometimes a substance simply stops being effective for reasons unrelated to a physiological tolerance mechanism.
This does not guarantee that a substance is being misused. Tolerance can develop even when a substance is used as prescribed or intended.
Scope
This information provides reference material only and does not constitute professional medical or psychological advice.